What are umbilical cord mesenchymal stem cells?
Umbilical cord mesenchymal stem cells (MSCs) are a kind of pluripotent stem cells existing in the umbilical cord tissue of newborn babies, which can be induced to differentiate into many kinds of tissue cells under a specific environment, and have a broad clinical application prospect.
Mesenchymal stem cells (MSCs) are another hotspot of scientific research after embryonic stem cells and haematopoietic stem cells, and they are a kind of ‘practical stem cells’ capable of treating a variety of systemic diseases.
1999 year
HORWITZ et al. Treatment of paediatric osteogenesis imperfecta and type I collagen deficiency with mesenchymal stem cells in the USA.
2002 year
O-N-KOC et al. treat mucopolysaccharidosis with mesenchymal stem cells in the US.
2003 year
Italy's MAZZINI et al. treat myotonic dystrophy lateral sclerosis with mesenchymal stem cells FOUILLARD et al, France, treat aplastic anaemia with mesenchymal stem cells
2005 year
Mesenchymal stem cell therapy for necrosis of the femoral head in the United States.MSCs are used to treat stroke in Korea.Russia M-F-RASULOV and others use MSCs to treat skin burns. 18 patients with reoccurring anaemia were treated with mesenchymal stem cells from the Twelfth People's Hospital of Guangzhou, with an overall effective rate of 72.2 per cent
2011 year
The use of mesenchymal stem cells to treat 229 patients with cerebral palsy in the PLA 463 Hospital has improved the patients' ability to perform their daily lives, with significant results.
2015 year
Neural regeneration collagen scaffolds combined with mesenchymal ubiquitous cells enter clinical studies for spinal cord injury treatment.
Uses of umbilical cord MSCs:
Mesenchymal stem cells (MSCs) are derived from embryonic tissues in the early stages of development, and are pluripotent stem cells, so named because they are found in human mesenchymal tissues. They have the characteristics of multi-directional differentiation potential, hematopoietic reconstruction support and promotion of stem cell implantation, immune regulation and self-replication, etc. They can be induced in vivo or in vitro by specific triggers. Under specific induction conditions in vivo or in vitro, they can be differentiated into bone, cartilage, muscle, tendon, ligament, nerve, liver, myocardium, blood vessel, epithelium, endothelium, fat and other tissues, and they still have multidirectional differentiation potential after successive passaging cultures and cryopreservation, so they can be used as ideal seed cells for repairing tissues and organs caused by aging and lesions.
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